Aseprite

Draw pixel art and animate sprites frame by frame, with layers, onion skin and tilemaps, then export GIFs and sprite sheets. For Windows, Mac and Linux, $19.99 once.

• Animated sprites with layers, frames and tags
• Onion skin and ping-pong playback
• Pixel-perfect strokes and shading ink
• Exports GIFs, sprite sheets and JSON
• Paid once: $19.99 for Windows, Mac and Linux

• Fixed a crash when pasting tilemaps, and copying tilemaps between layers and sprites works better
• Sprite sheet JSON escapes line breaks in exported user data
• Linux: better window resizing and Ctrl shortcuts on X11